Niadyne Skin Care Review


Niadyne Skin Care Review


Quick Overview
  • Difficulty
  • Cost
  • Trial Period
    30 Days

Niadyne is a scientifically-based skin and beauty product manufacturer with a headquarters in North Carolina and research laboratories in Tucson, Arizona.

The company was founded in 1997 by Elaine and Myron Jacobson, both of whom hold PhDs in biochemistry from Kansas State University.

In addition to running Niadyne, the Jacobsons currently serve as professors at the College of Pharmacy within the University of Arizona, and both possess memberships with the Arizona Cancer Center.

Niadyne offers a line of skincare products known as NIA24, the culmination of over 25 years of painstaking biomedical research. The entire product line is based on a patented version of Niacin, also known as Vitamin B3, entitled "Pro-Niacin." A complete overview of how Pro-Niacin was developed and why it's so effective in addressing a wide variety of skincare concerns is provided at the Niadyne website.

Niadyne's products have received a plethora of positive reviews from both consumers and medical professionals alike, many of which are posted on the Niadyne website. As you may expect, these premium skincare products come with an above-average price tag. However, a number of deep discounts are available when you purchase the company's products from, one of Niadyne's primary online distributors.

The company also offers unlimited 10% discounts for email newsletter subscribers, free shipping on orders with a value over $49, free sample products and a variety of other sales and promotions. also offers customer support via live chat, phone and email thanks to a team of licensed estheticians.


    • Extensive research and clinical testing.
    • Highly focused product line.
    • Thorough product information on website.
    • Recommended by skincare professionals.
    • Excellent user testimonials.
    • Strong customer support via phone and live chat.
    • Free shipping on orders over $49.


    • Relatively expensive.
    • Some artificial ingredients, including parabens.


Niadyne makes up for a limited product line with exceptional quality. NIA24 comprises a cleansing cream, sunscreens, exfoliating serums, a strengthening complex, a recovery complex and more. All of the products are extensively tested before they're brought to market, which may explain why the company has chosen to include less than 10 items in its entire product catalog. Although Niadyne's products are relatively expensive, they're designed to last a long time, with a shelf life of 3 years for most products and 2 years for sunscreens.

Niadyne's NIA24 skincare product line is incredibly safe and compatible with a wide variety of other skin and beauty products despite it's prescription-level efficacy and strength. It's impossible to apply an unsafe amount of the company's products, as Pro-Niacin is completely water-soluble, and any excess amount will be flushed away from the skin without a risk of toxicity. Further, the products are compatible with all skin types, including sensitive, oily and dry. Although the products are not designed to treat acne, they do not exacerbate existing breakouts or clog pores.

Niadyne maintains some of the highest quality product pages of any online skincare company. Each product page includes a full list of ingredients, a detailed FAQ exclusive to that product, and general FAQs relating to the product line in general and Pro-Niacin, the common active ingredient, in particular. The product pages also include extremely detailed usage guidelines in the form of both an Intro Regimen and a Daily Regimen. You can greatly enhance the effectiveness of the products by using these suggested regimens in combination with the advice of your skincare professional.


All of Niadyne's skincare products include the ingredient Pro-Niacin, a modified version of Vitamin B3 that has been proven to stimulate the repair of DNA while building a skin barrier from inside of the skin. Pro-Niacin also stimulates Leptin release, facilitates energy metabolism and modulates blood cholesterol levels.

Niadyne offers a full list of ingredients on each individual product page. This is greatly beneficial to those seeking total product transparency, and can prevent a potentially dangerous incident for those who suffer from allergies. Ingredient lists are also readily available on the NIA24 product pages found on

Niadyne provides a Glossary of Terms within their FAQ section that offers definitions and additional information regarding some of the products that are most prominently featured in their product catalog. This is an excellent resource for those who want to know more about exactly what they're applying to their skin.

It should be noted that Niadyne is not an all-natural skincare company, and some of their products do contain artificial preservatives, emulsifiers and other additives. However, none of the products contain artificial fragrances or dyes, greatly reducing the chances of skin irritation. The sunscreens, for example, are physical instead of chemical, meaning that they sit on top of your skin instead of absorbing into it. This further reduces the chances of unwanted side effects.

Clinical Studies and Research

Niadyne takes an extremely serious approach to clinical testing and scientific research, which customers can verify by visiting the Clinical Studies area of the Niadyne website located within the Science section. Here, you'll find a number of peer-reviewed medical articles that are updated and added to on a regular basis. The articles are extremely in-depth, with titles such as "Cellular NAD Status as a Regulator of Photodamage" and "A Pilot Study Evaluating the Efficacy of Topically Applied Niacin Derivatives for Treatment of Female Pattern Alopecia." Although these clinical trials may be difficult for the average skincare product consumer to comprehend, it's reassuring to know that Niadyne is more than willing to fully reveal the science behind their skin and beauty products. Niadyne has stated that they'll add more clinical trials to the already-extensive list as they become available.

The Before and After Photos section of the Niadyne website's Science area includes actual photos of trial subjects before and after using the products from Niadyne, including creams, serums and others. Some of the photos represent a trial period of 40 days while others extend to 90 days or longer, indicating that the products are truly effective with continued application as directed.

Niadyne's commitment to research and development is obvious in the content of their website. Roughly fifteen pages of text and diagrams are devoted to a complete scientific description of Pro-Niacin, the patented molecule that's included in all of the products from Niadyne. This guide describes exactly how Pro-Niacin benefits the skin, with extensive details regarding absorption, functions, enhanced biochemical mechanisms and ultimately, results after the use of a suggested regimen.


The effectiveness of the products sold by Niadyne can be measured in several ways, chief of which are the testimonials found directly on the company's website. The testimonials are divided into two categories: those from consumers, of which there are over 80, and those from physicians, of which there are 8. Several of these testimonials describe the effectiveness of specific products sold by Niadyne, while others simply state their satisfaction with the company in general. The physicians' testimonials are particularly intriguing, as they confirm that plenty of dermatologists and other medical doctors actually prescribe Niadyne products to their patients for a variety of conditions.

If you're looking for user testimonials that are attached to specific products, you can find them by viewing the Niadyne product pages found at Although some of the products only have a view testimonials, virtually all of the reviews are extremely positive, with consumers praising the Niadyne product line for its effectiveness, consistency and tendency to not irritate the skin. Some of these testimonials once again confirm that Niadyne products are indeed prescribed by licensed dermatologists. As opposed to the testimonials found on the Niadyne website, some of the testimonials are quite critical. While these are few and far between, they do assist customers with product selection and serve as a second opinion, pointing out the disadvantages of a given product as well as the obvious benefits.

Customer Support is a massive online skincare product retailer capable of offering some of the most knowledgeable and comprehensive customer support in the industry. As expected, they offer several different forms of direct customer service including live chat, email and phone, all of which are available free of charge. Phone support is provided on weekdays, 7:00am through 7:00pm MT, and on Saturday between the hours of 9:00am and 2:00pm MT. Live chat, which is provided during the same hours, is available under the Live Help link found on the customer support area. In order to access live chat, you'll need to enter your name, email address and a description of the problem you're encountering. maintains a customer support team comprising licensed estheticians capable of answering virtually any questions regarding skin conditions, beauty concerns, product formulations and more. This represents a much deeper level of service than what you'll find at most skincare product retailers, whose live support technicians are usually only capable of giving basic product advice and information regarding shipping, accounts and orders. When purchasing expensive skincare products from companies such as Niadyne, this type of customer support is invaluable.

The website contains plenty of other customer service provisions, such as a detailed FAQ section, a Skin Care Dictionary and an articles database featuring skincare news and insights from professional estheticians. The Skin Care Dictionary is excellent by itself, as it offers definitions of virtually all of the ingredients you'll likely find in products from Niadyne and others.

Product Return Policy offers a 30-day return policy on all products sold by Niadyne and the other skincare manufacturers they carry. This policy lets you try Niadyne products for up to a month before deciding whether to exchange, return or keep the item. Exchanges are available for products that are sent incorrectly, as well as those that arrive defective or damaged. Alternatively, you may seek a refund for any product that causes a negative skin reaction, or for any product that you're simply dissatisfied with. By returning a Niadyne product to for a refund, you'll receive full repayment minus the cost of shipping. However, choosing an exchange instead will effectively allow you to save on the cost of shipping a second item. Customers should note that only products with 50% or more of their contents remaining are eligible for a refund. This prevents you from using an entire bottle of product and later claiming dissatisfaction.

In order to return a Niadyne product to for a refund or exchange, you must first obtain a return authorization from the latter company's customer service department. It's advisable to ship the item(s) securely via a method such as UPS or FedEx with both shipping tracking and shipping insurance, since any damage incurred during return transit could result in a loss of your refund. states that they may deny refund requests from individuals who repeatedly attempt to return the same products.


Niadyne is a premium skincare product manufacturer, with product prices at or slightly above what you'd expect from this tier of the skin and beauty industry. Fortunately, some of the company's products are more affordable, making the overall Niadyne product line slightly more accessible to average consumers. For example, the Niadyne Intensive Recovery Complex hydrating treatment costs $108.90 for 1.7 oz., while the Physical Cleansing Scrub is available for a relatively inexpensive $34.70 for 3.75 oz. Although Niadyne skincare products are undoubtedly more expensive than what you may be accustomed to, scientifically verified results lie behind all of the company's products, thereby creating an excellent value regardless of the sticker price.

By purchasing Niadyne skin and beauty products from, you'll receive a number of money-saving perks that can greatly increase the affordability of the company's product line. Those who sign up for the email newsletter will receive a 10% discount off of every single order, even for products that are currently on sale or clearance. By placing an order of a certain minimum qualifying amount, you'll be able to select from a number of free gifts including product samples, cosmetics bags and health and beauty accessories. ships all orders over $49 free of charge within the contiguous United States. also offers a virtually unprecedented Price Matching Guarantee. This policy allows the company to match the advertised prices of its competitors on products from Niadyne and other manufacturers. When a competing retailer offers a lower price resulting from a sale, cashback rewards program or a free shipping offer, will still match it. This program is even more beneficial than it first appears, as it gives you the convenience of shopping for skincare products in one central location, thereby saving on shipping costs.


Niadyne is a premium skincare product manufacturer with a focused product line based on Pro-Niacin, a patented ingredient that provides a plethora of proven benefits to the skin. All of Niadyne's products are formulated by Myron and Elaine Jacobson, two biochemists that founded the company in 1997. The Jacobsons' research has resulted in a line of skincare products virtually unparalleled in terms of proven effectiveness and backing scientific research. Unlike many skincare companies, Niadyne makes this research available to the public in its unedited form directly on its website.

Niadyne does have a few disadvantages, namely that the products contain some artificial ingredients, and that they're somewhat expensive compared the offerings of many premium skincare manufacturers. However, the NIA24 product line easily compensates by comprising some of the most effective and well-researched products on the market. When combined with the rotating and regular sales and excellent customer support of online retailer, the skincare products offered by Niadyne are actually an excellent value. A 30-day no-questions-asked return policy is just one more reason to audition the company's products.